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| Player | Rushing TDS |
|---|---|
| Jonathan Taylor | 18 |
| Derrick Henry | 16 |
| Jahmyr Gibbs | 13 |
| Josh Jacobs | 13 |
| James Cook | 12 |
| Kyren Williams | 12 |
| Zach Charbonnet | 12 |
| Javonte Williams | 11 |
| Christian McCaffrey | 10 |
| D'Andre Swift | 10 |
| Kenneth Walker III | 9 |
| TreVeyon Henderson | 9 |
| Kareem Hunt | 8 |
| De'Von Achane | 8 |
| David Montgomery | 8 |
| Jacory Croskey-Merritt | 8 |
| Tyler Allgeier | 8 |
| Bijan Robinson | 7 |
| RJ Harvey | 7 |
| Rhamondre Stevenson | 7 |
| Saquon Barkley | 7 |
| Sean Tucker | 7 |
| Quinshon Judkins | 7 |
| Travis Etienne | 7 |
| Chris Rodriguez Jr. | 6 |