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Top 5 by EPA per Play: 1. Brian Robinson (1.686 EPA per Play); 2. Alvin Kamara (0.541 EPA per Play); 3. Kendre Miller (0.528 EPA per Play); 4. Omarion Hampton (0.377 EPA per Play); 5. James Cook (0.331 EPA per Play).
| # | Player | EPA per Play | Rush Attempts | Rushing Yards | Rushing TDS |
|---|---|---|---|---|---|
| 1 | Brian Robinson | 1.686 | 5 | 37 | 4 |
| 2 | Alvin Kamara | 0.541 | 5 | 10 | 2 |
| 3 | Kendre Miller | 0.528 | 6 | 21 | 2 |
| 4 | Omarion Hampton | 0.377 | 14 | 52 | 3 |
| 5 | James Cook | 0.331 | 18 | 64 | 5 |
| 6 | Bucky Irving | 0.282 | 12 | 48 | 2 |
| 7 | Ollie Gordon II | 0.281 | 15 | 54 | 3 |
| 8 | Kyren Williams | 0.263 | 17 | 48 | 4 |
| 9 | Chuba Hubbard | 0.255 | 10 | 41 | 3 |
| 10 | Woody Marks | 0.196 | 8 | 21 | 2 |
| 11 | Derrick Henry | 0.176 | 29 | 100 | 6 |
| 12 | Jahmyr Gibbs | 0.106 | 30 | 91 | 7 |
| 13 | Jonathan Taylor | 0.101 | 20 | 38 | 5 |
| 14 | Javonte Williams | 0.082 | 21 | 38 | 6 |
| 15 | Travis Etienne | 0.071 | 5 | 16 | 0 |
| 16 | Rachaad White | 0.060 | 4 | 8 | 0 |
| 17 | Braelon Allen | 0.053 | 5 | 16 | 1 |
| 18 | Christian McCaffrey | 0.044 | 14 | 22 | 5 |
| 19 | Bhayshul Tuten | 0.004 | 12 | 34 | 2 |
| 20 | Rhamondre Stevenson | -0.006 | 5 | 11 | 2 |
| 21 | MarShawn Lloyd | -0.046 | 11 | 27 | 2 |
| 22 | Jeremiyah Love | -0.048 | 11 | 30 | 1 |
| 23 | Kaelon Black | -0.071 | 7 | 18 | 0 |
| 24 | Bijan Robinson | -0.092 | 20 | 57 | 3 |
| 25 | Tank Bigsby | -0.119 | 5 | 13 | 1 |