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| Player | Avg Separation |
|---|---|
| Luther Burden III | 4.362 |
| Malik Washington | 4.129 |
| Marvin Mims Jr. | 3.917 |
| Khalil Shakir | 3.754 |
| Xavier Worthy | 3.729 |
| Zay Flowers | 3.644 |
| Tre Tucker | 3.609 |
| DJ Moore | 3.600 |
| Rashee Rice | 3.587 |
| Chimere Dike | 3.500 |
| Deebo Samuel Sr. | 3.438 |
| Wan'Dale Robinson | 3.429 |
| Jameson Williams | 3.209 |
| Ladd McConkey | 3.208 |
| Justin Jefferson | 3.200 |
| Ja'Marr Chase | 3.031 |
| Amon-Ra St. Brown | 3.025 |
| DeVonta Smith | 3.014 |
| Olamide Zaccheaus | 3.014 |
| Jaxon Smith-Njigba | 2.978 |
| Troy Franklin | 2.964 |
| Jordan Addison | 2.957 |
| Michael Pittman | 2.942 |
| Chris Olave | 2.940 |
| Marquise Brown | 2.900 |